We are seeking a computational biologist with expertise in making biological discoveries by leveraging large-scale genomic data to join Vertex’s research site in Boston, MA. This position is part of a growing global Computational Genomics team focused on developing gene editing and genetic therapy treatments of serious human diseases. Your key tasks will be to collaborate with cross-functional project teams to design studies, analyze and interpret large-scale genomics data, and communicate results that will have critical impact on the development of cutting-edge, transformative therapies. You will play a key role in bringing together the needs of project teams with state-of-the-art computational biology tools, which will require proactive communication and seamless collaboration with both computational and experimental team members.
Collaborate with project teams, acting as the computational biology expert, to identify key needs and questions that can be addressed using genomics, sequencing, or bioinformatics contributions
Plan studies leveraging sequencing, genetic, and genomic data to answer biological questions and enable development of genetic therapy treatments
Plan, execute, and iterate on analysis of large-scale sequencing data, in partnership with computational and experimental team members
Visualize, summarize, and communicate findings to project teams and other key stakeholders
Follow cutting-edge advancements in the fast-paced fields of gene editing and genetic therapies, bringing developments in-house or building upon them as appropriate
Partner with method development team members to improve or expand computational methods
PhD degree in computational biology, bioinformatics, human genetics, genomics, systems biology, bioengineering, or a related field
A proven track record in the analysis, visualization, and interpretation of genomic and next-generation sequencing (NGS) data
Demonstrated ability to work closely with project teams and/or experimental collaborators to design studies and develop analyses to answer scientific questions
Solid scientific understanding of gene editing, the role of genetic variation in human disease, molecular biology, and cellular biology
Expertise with applying computational methods and bioinformatics tools to large-scale data; proficiency with R, Python, Linux/Unix systems, high-performance computing systems; solid understanding of statistics
Detail-oriented and self-motivated approach to problem solving with excellent reasoning skills
A team-oriented growth mindset that welcomes feedback from others and supports other team members; strong collaboration skills to work across teams and functions
A positive attitude that enthusiastically tackles and overcomes challenges
Strong organizational and time-management skills to prioritize needs and get things done
Excellent presentation and communication skills, including the ability to tailor scientific content to audiences with different backgrounds
Internal Number: 12112BR
About Vertex Pharmaceuticals
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases.
Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston's Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 2,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development.
Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and t...he British Pharmacological Society awards. For additional information and the latest updates from the Company, please visit www.vrtx.com.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.