At Quest, we are on a continuous journey of discovery and development. It’s this attitude that has made us an industry leader and the #1 Diagnostic Lab in the US. For those joining us, we offer exciting and fast-moving career opportunities where you can affect change at a rate unheard of in many organizations of our size and scope. While we invest in and develop technology to drive our innovations, our ongoing success relies on our people.
As a Bioinformatics/Computational Biology Scientist, you will work for the world leader in the industry, with a career where you will have the opportunity to collaborate and affect change while expanding your leadership skills and technical knowledge.
This professional will work from one of the following offices: Lewisville, TX; San Juan Capistrano, CA or Marlborough, MA.
Bioinformatics/Computational Biology Scientist, the role:
Medfusion is a Quest Diagnostics Precision Oncology Center of Excellence and a full-service laboratory and clinical trials service organization. Our core oncology products provide specific answers that clinicians need to deliver the appropriate diagnostic and/or prognostic care to oncology patients throughout the United States.
As a member of the Medfusion/Quest Diagnostics Bioinformatics team, you will focus on general bioinformatics/computational biological needs of the company, interfacing with both R&D and clinical operations. On the R&D side, your projects will revolve around new product development that requires massive data profiling and use these features to generate standardized data sets. Standardized data sets are crucial for rapid pipeline development, timely product releases, and reduced validation costs. On the clinical side, you will support Technical and Scientific Directors to resolve challenging cases, provide ad hoc data queries and troubleshoot issues arising with our clinical workflows when needed.
Work in collaboration with key scientific personnel and the Bioinformatics Pipeline Engineer to build, test, adapt, support and validate clinical-grade variant analysis pipelines
Profile NGS data (Illumina/ThermoFisher) for platform-specific patterns and synthetic data modeling
Create standardized NGS datasets to be used throughout testing and validation of our ever-expanding clinical-grade pipelines across multiple sites
Support R&D and clinical operations with ad hoc data queries, troubleshooting database and data-flow issues
Aid in the design and implementation of bioinformatic databases
Report directly to the Bioinformatics Scientific Director
To qualify, the ideal candidate will have the following skills and experience:·
Demonstrated proficiency in algorithm development for the analysis of large NGS datasets
Demonstrated proficiency in presenting massive amounts of data in a clean and functional way;
Demonstrated proficiency in manipulating large NGS datasets: data transformation, read trimming, alignment, variant calling, and data store migration
Proficiency working in Unix/Linux operating systems (BASH scripting and command-line tools)
Proficiency in commonly used command-line NGS tools (BWA, SAMTools, Bowtie2, Picard, PINDEL, GATK, etc.)
Ability to understand and communicate statistical measures for interrogating the quality of data manipulation
Demonstrated ability to communicate efficiently and work effectively with a team of scientists
Demonstrated capacity for innovation
Experience with software development best practices: unit testing, issue tracking, software life cycle, and shared code repositories;
Experience preparing documentation in support of CAP/CLIA certification
Experience with version control systems such as Git
Familiarity with various assays, sequencing techniques (RNA-seq, WES, WGS), and sequencing technologies from companies such as Illumina, ThermoFisher, and PacBio
Experience with distributed resource managers/schedulers like Univa/Sun Grid Engine (UGE/SGE) or TORQUE
B.S. with 6+ years of experience in Bioinformatics, Genomics, Genetics, Computer Sciences or a related field, or M.S. with 4+, or Ph.D. with 2+ years of experience, or equivalent
Join us for competitive benefits and development opportunities in a progressive and supportive environment. Help us improve our service, and the experiences of our patients and colleagues. Work with us and together we can be better.
Your Quest career. Seek it out.
All requirements are subject to possible modifications to reasonably accommodate individuals with disabilities. Quest Diagnostics is an Equal Opportunity Employer: Women / Minorities / Veterans / Disabled / Sexual Orientation / Gender Identity.
Internal Number: req33640
About Quest Diagnostics
We are an industry leader with a longstanding reputation for exceptional quality and stability in our market. We inspire action, illuminate answers, and advocate better health.
At Quest Diagnostics, we are dedicated to continuously improving patient health. We are the world’s leading provider of diagnostic testing, services, and information that patients and doctors rely on to make better healthcare decisions.
Each day, we impact the lives of millions, serving one in three American adults. Our continuous pursuit to discover and innovate enables us to create new solutions every day, many of which are now industry standards of care. Diagnostic tests influence about 66% of clinical decision making.